Munjal Acharya has been working the field of regenerative medicine and cancer therapy- induced brain injury for the past ten years. Dr. Acharya has uncovered glia-dependent pathophysiological mechanism of radiation-induced cognitive dysfunction. In addition, Dr. Acharya has developed human stem cell-based regenerative strategies to remediate brain from the unintended side-effects of cancer therapies including cranial irradiation and chemotherapy. His research has delineated paracrine mechanism (exosomes) of stem cell transplantation- mediated recovery of the injured brain.
Dr. Acharya received his Ph.D. degree in neurochemistry from M. S. University of Baroda (India). His interests in neuroscience continued as a postdoctoral researcher at Duke University Medical Center (US) to study the efficacy of stem cell grafting to treat epilepsy. Dr. Acharya then joined University of California Irvine as a CIRM postdoctoral fellow. Currently, Dr. Acharya’s laboratory studies molecular and cellular mechanisms of cancer therapy-induced brain injury, regenerative therapies for Alzheimer’s disease and HIV-associated neurocognitive disorders.
Research in Lay Terms
The focus of my laboratory’s research is to define the molecular and cellular mechanisms that glial signaling response following cancer therapy-related brain injury, Alzheimer’s disease and HIV-related cognitive impairments.